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KMID : 1103720210820020487
Journal of the Korean Society of Radiology
2021 Volume.82 No. 2 p.487 ~ p.492
Unusual Manifestation of Immunoglobulin G4-Related Disease Involving the Retroperitoneum: A Case Report
Kim Byung-Soo

Seo Jung-Wook
Abstract
Immunoglobulin G4 (IgG4)-related disease is a systemic disease characterized by dense lymphoplasmacytic infiltrates with abundant IgG4-positive plasma cells and fibroblast proliferation. The retroperitoneal involvement of IgG4-related disease usually appears as a soft-tissue mass covering the abdominal aorta or entrapping the ureters, resulting in hydronephrosis. Here, we present a case of IgG4-related disease with retroperitoneal involvement in a 75-year-old woman with an unusual manifestation. A preoperative computed tomography (CT) scan revealed an irregular infiltrative retroperitoneal mass invading the normal anatomic barriers, raising the suspicion of malignancy or inflammation. Contrast-enhanced CT revealed a homogeneous progressive enhancement of the mass.
KEYWORD
Immunoglobulin G4-Related Disease, Retroperitoneal Space, Computed Tomography, X-Ray
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